Respiratory and Quadriceps Muscle Fatigability After an ICU Acquired Weakness

G

Groupe Hospitalier du Havre

Status

Enrolling

Conditions

ICU Acquired Weakness

Treatments

Diagnostic Test: Muscle evaluation

Study type

Observational

Funder types

Other

Identifiers

NCT05396066
2021-A02816-35

Details and patient eligibility

About

Muscle dysfunction can be lead to poor outcomes moreover ICU muscle weakness recovery are not correctly described. The investigators aimed to assess the ability for quadriceps or respiratory muscles to repeat an effort at a maximal loading.

Enrollment

20 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Mechanically ventilated at least at 24 Hours
  • Maximal inspiratory pressure < 30 centimeter of water
  • MRC score < 48/60

Exclusion criteria

  • Age < 18 years
  • Patients with neurological pathology or pre existing neuromuscular dysfunction
  • Patient unable to walk 50 meters before ICU admission
  • Patient with a thoracic or abdominal surgery
  • Inability to carry out maximal voluntary contraction

Trial contacts and locations

0

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Central trial contact

Clement Medrinal, PhD; Yann Combret, PhD

Data sourced from clinicaltrials.gov

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