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Respiratory Function, Exercise Capacity and Peripheral Muscle Strength Among Patients With CF, PCD and Healthy Children

B

Bezmialem Vakif University

Status

Completed

Conditions

Primary Ciliary Dyskinesia
Cystic Fibrosis

Treatments

Other: pulmonary function test
Other: Measurement of functional capacity
Other: Respiratory muscle strength
Other: Peripheral muscle strength
Other: Functional capacity

Study type

Observational

Funder types

Other

Identifiers

NCT04161313
hdenizkulli2

Details and patient eligibility

About

The aim of this study is to compare pulmonary function, respiratory muscle strength, exercise capacity and peripheral muscle strength of patients with CF, PCD and healthy childrens.

Full description

The impaired airway clearence and pulmonary functions, exercise intolerance, low physical activity level and decreased peripheral muscle strength make physiotherapy approaches important in the management of CF and PCD.

Enrollment

76 patients

Sex

All

Ages

6 to 18 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Diagnosis of cystic fibrosis or primary ciliary dyskinesia

Exclusion criteria

  • Hospitalization history in past month
  • Diagnosis of other chronic pediatric diseases which may impair exercise tolerance such as cerebral palsy or neuromuscular disease
  • Candidates for lung transplantation or history of lung transplantation

Trial design

76 participants in 3 patient groups

Cystic fibrosis
Description:
children with cystic fibrosis
Treatment:
Other: pulmonary function test
Other: Measurement of functional capacity
Other: Respiratory muscle strength
Other: Peripheral muscle strength
Other: Functional capacity
primary ciliary dyskinesia
Description:
children with primary ciliary dyskinesia
Treatment:
Other: pulmonary function test
Other: Measurement of functional capacity
Other: Respiratory muscle strength
Other: Peripheral muscle strength
Other: Functional capacity
healthy controls
Description:
Age-matched healthy volunteers
Treatment:
Other: pulmonary function test
Other: Measurement of functional capacity
Other: Respiratory muscle strength
Other: Peripheral muscle strength
Other: Functional capacity

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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