Respiratory Muscle Contribution to Blood Pressure During Exercise

Mayo Clinic

Status: Completed

Conditions: Sympathetic Nerve Activity; Exercise Capacity; Respiratory Muscle; Blood Pressure

Treatments: Other: No Inspiratory Muscle Training (IMT); Other: Inspiratory Muscle Training (IMT)

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT03514823

5R01HL126638-03 (U.S. NIH Grant/Contract)

17-011100

Details and patient eligibility

About

The investigators seek to understand how reflexes from the breathing muscles influence blood pressure during exercise. Furthermore, the investigators are determining if increasing breathing muscle strength (via inspiratory muscle training) influences the respiratory muscle contribution to blood pressure during exercise.

Enrollment: 38 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Healthy participants with no history of cardiovascular, pulmonary, neurologic, orthopedic or other neuromuscular diseases.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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38 participants in 2 patient groups

IMT Group

Experimental group

Treatment:

Other: Inspiratory Muscle Training (IMT)

No IMT Group

Sham Comparator group

Treatment:

Other: No Inspiratory Muscle Training (IMT)