Respiratory Muscle Strength in Patients With NMD (RMST)

University of Florida

Status: Terminated

Conditions: Neuromuscular Disease

Treatments: Device: Threshold PEP or IMT device Phillips-Respironics

Study type: Interventional

Funder types: Other

Identifiers

NCT01555905

IRB201600270

Details and patient eligibility

About

The purpose of this study is to determine if inspiratory muscle strength training (IMST) will impact maximal inspiratory pressure and pulmonary function in patients with neuromuscular disease.

Full description

Subjects undergo a 12-week period of inspiratory muscle strength training. Respiratory strength is assessed before and after the training period.

Enrollment: 17 patients

Sex: All

Ages: 6 months to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Confirmed diagnosis of neuromuscular disease
• Clinical evidence of impaired pulmonary function

Exclusion criteria

• Above or below age range
• No clinical evidence of impaired pulmonary function
• No diagnosis of a neuromusuclar disease
• Presence of an acute illness at time of study
• Participating in other research studies involving investigational drugs
• Diagnosis of a primary pulmonary disease
• Use of tobacco products

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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17 participants in 1 patient group

Exercise

Experimental group

Description:

Threshold PEP or IMT device Phillips-Respironics

Treatment:

Device: Threshold PEP or IMT device Phillips-Respironics