Respiratory Muscle Stretching Exercise for Improving Quality of Life of Patients With Bronchiectasis

Universitas Padjadjaran

Status: Completed

Conditions: Bronchiectasis Post-Tuberculosis Lung Disease

Treatments: Other: Standard PR plus Respiratory Muscle Stretching; Other: Standard PR

Study type: Interventional

Funder types: Other

Identifiers

NCT06722547

IKFR-202411.04

Details and patient eligibility

About

Bronchiectasis is a chronic condition often arising after the successful treatment of lung tuberculosis, leading to diminished functional exercise capacity, increased fatigue, and reduced quality of life. This randomized controlled trial aims to evaluate the efficacy of adding Respiratory Muscle Stretching (RMS) exercises to standard pulmonary rehabilitation in improving functional exercise capacity, reducing fatigue, and enhancing the quality of life in patients with bronchiectasis post-tuberculosis.

Full description

Bronchiectasis, a long-term sequelae of lung tuberculosis, is characterized by permanent dilation and damage of the bronchi, resulting in reduced lung function, persistent fatigue, and significantly impaired quality of life. Standard pulmonary rehabilitation (PR) programs, which include aerobic exercises and breathing techniques like Pursed Lip Breathing (PLB) and the Active Cycle of Breathing Technique (ACBT), are known to offer symptomatic relief and functional improvements. However, the role of Respiratory Muscle Stretching (RMS) in this context has not been well explored.

This clinical trial will assess the impact of RMS, when combined with standard PR, on key outcomes including functional exercise capacity, fatigue, and overall quality of life in patients with bronchiectasis following tuberculosis treatment. The study will involve a parallel assignment of patients to either the standard PR group or the PR plus RMS group, with outcomes measured over a 6-week intervention period. The primary endpoints will include changes in 6-Minute Walk Test (6MWT) distances, Fatigue Severity Scale (FSS) scores, and Quality of Life (St. George's Respiratory Questionnaire) scores.

Enrollment: 50 patients

Sex: All

Ages: 18 to 59 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-59 years
• History of lung TB treatment
• Clinical or radiological diagnosis of bronchiectasis
• mMRC Dyspnea Scale grade 1-3

Exclusion criteria

• Pneumothorax Pleural effusion
• Neuromuscular disease
• Lung malignancy
• history of COVID-19

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Group A (Standard Pulmonary Rehabilitation)

Active Comparator group

Description:

Aerobic exercise, PLB, ACBT, Education

Treatment:

Other: Standard PR

Group B (Standard PR + RMS)

Experimental group

Description:

Standard PR plus Respiratory Muscle Stretching

Treatment:

Other: Standard PR plus Respiratory Muscle Stretching