Respiratory Oscillometry for the Prediction of Bronchopulmonary Dysplasia (REACT)

Fondazione IRCCS San Gerardo dei Tintori

Status: Enrolling

Conditions: Bronchopulmonary Dysplasia

Treatments: Diagnostic Test: Respiratory Oscillometry

Study type: Observational

Funder types: Other

Identifiers

NCT05986032

REACT

Details and patient eligibility

About

The goal of this observational study is to learn about the correlation between respiratory system reactance, as assessed by respiratory oscillometry, and respiratory outcomes in preterm infants born before 32 weeks of gestation. The main question it aims to answer is if the reactance z-score at 7 postnatal days adds to relevant clinical factors in the prediction of bronchopulmonary dysplasia. Participants will receive respiratory oscillometry measurements at 7 ± 2 postnatal days.

Enrollment: 150 estimated patients

Sex: All

Ages: 5 to 9 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

• born before 32 weeks post-menstrual age

Exclusion criteria

• congenital abnormalities
• Inherited disorders of metabolism

Trial design

150 participants in 2 patient groups

no bronchopulmonary dysplasia

Description:

Group of patients who do not receive the diagnosis of bronchopulmonary dysplasia defined as the need for respiratory support at 36 weeks post-mentrual age

Treatment:

Diagnostic Test: Respiratory Oscillometry

bronchopulmonary dysplasia

Description:

Group of patients developing bronchopulmonary dysplasia defined as the need for respiratory support at 36 weeks post-menstrual age.

Treatment:

Diagnostic Test: Respiratory Oscillometry