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Respiratory Outbreak Mitigation in Long-Term Care Using Point-of-Care Testing (PROMPT-LTC)

M

Michael Garron Hospital

Status

Enrolling

Conditions

Outbreaks

Treatments

Device: Point-of-care respiratory test platform
Other: Existing respiratory virus testing platform

Study type

Interventional

Funder types

Other

Identifiers

NCT06660433
CK-19-2024

Details and patient eligibility

About

Outbreaks of seasonal respiratory viruses can spread rapidly in long-term care homes. Timely results for diagnostic tests remains a challenge for respiratory viruses due to the logistics of using a reference laboratory with delays leading to missed opportunities to implement virus-specific control measures to interrupt transmission resulting in larger outbreaks. Use of a point-of-care testing platform is a potential solution that provides faster results, but it is uncertain whether this translates into benefits for long-term care residents. This trial aims to assess whether rapid test results for respiratory pathogens (Influenza, Coronavirus disease of 2019 (COVID-19) and Respiratory Syncytial Virus) can impact the number and size of respiratory virus outbreaks in long-term care homes.

Enrollment

24 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

- Long-term care facility engaged with an Ontario Health Team overseen by Sunnybrook Health Science Centre, Michael Garron Hospital or Humber River Health

Exclusion criteria

  • No signed statement of agreement for study participation
  • Pre-existing use of a point-of-care testing platform

Trial design

Primary purpose

Health Services Research

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

24 participants in 2 patient groups

Point-of-Care Polymerase Chain Reaction Testing Platform
Experimental group
Treatment:
Device: Point-of-care respiratory test platform
Existing Testing Platform for Respiratory Viruses
Active Comparator group
Treatment:
Other: Existing respiratory virus testing platform

Trial contacts and locations

2

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Central trial contact

Jerome Leis, MD, MSc; Christopher Kandel, MD, PhD

Data sourced from clinicaltrials.gov

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