Respiratory Therapy in COPD Exacerbations (TRESEPOCAS)

Parc de Salut Mar

Status: Completed

Conditions: Obstructive Chronic Bronchitis With Acute Exacerbation

Treatments: Other: Respiratory Therapy; Other: No Respiratory Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT02125747

PSM/RHB/CR/05

Details and patient eligibility

About

The purpose of this study is to determine effectiveness, feasibility and safety/tolerance of Respiratory Therapy in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease.

Full description

Acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) is defined as an event in the natural course of the disease characterized by a change in the patient's usual symptoms (dyspnea, cough and/or sputum) that may not be explained by the daily variations and requires a change in regular medication.

Because AE-COPD result in impairment of both pulmonary and respiratory muscle functions, as well as an increasing impact on costs, priority should be given to interventions to slow the progression of the disease, prevention of exacerbations and reduce the risk of comorbidity.

Chest physiotherapy is often used in hospitalized patients with AE-COPD with the aim of favoring the removal of secretions and thus to improve the ventilation perfusion (V/Q), and therefore the function lung. The limited scientific evidence has determined that their use is controversial and not routinely recommended in clinical practice guidelines. Current clinical guidelines in the treatment of COPD are unable to rule on the application of respiratory therapy during exacerbations, since there is little scientific evidence of its benefits in the short and long term.

Enrollment: 35 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Hospitalized patients with acute exacerbation of COPD.

Inclusion Criteria:

• age over 18 years,
• hospitalized patients and
• acute exacerbation of COPD.

Exclusion Criteria:

• Previous history of any chronic respiratory disease and
• not to have performed any kind of general or respiratory training in the previous 3 months.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

35 participants in 2 patient groups

No Respiratory Therapy

Other group

Description:

Patients with acute exacerbation of chronic obstructive pulmonary disease. Patients received conventional treatment.

Treatment:

Other: No Respiratory Therapy

Respiratory therapy

Experimental group

Description:

Patients with acute exacerbation of chronic obstructive pulmonary disease. Patients received conventional treatment and Respiratory Therapy

Treatment:

Other: Respiratory Therapy