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Respiratory Training in Hemodialysis Patients

F

Faculdade de Ciências Médicas da Santa Casa de São Paulo

Status

Completed

Conditions

Chronic Kidney Diseases

Treatments

Other: Respiratory muscle training

Study type

Interventional

Funder types

Other

Identifiers

NCT03153124
64024117.4.0000.5479

Details and patient eligibility

About

Patients with chronic kidney disease in hemodialysis have complex syndrome with diverse effects on cardiovascular, nervous, respiratory, musculoskeletal, immune and endocrine-metabolic systems. With regard to the musculoskeletal structure, there is progressive muscular loss with consequent increase in muscle weakness, limited resistance, exercise intolerance and fatigue, as well as functional and morphological abnormalities characteristic of uremic myopathy. Respiratory muscles are also affected as a result of uremic myopathy, with decreased strength and resistance. Objective: to analyze the impact of respiratory muscle training on muscle strength, functional capacity and quality of life of patients with chronic kidney disease on hemodialysis. Method: This is a prospective, randomized study involving 46 patients followed by the dialysis unit of a university hospital, over 18 years old, of both genders who underwent hemodialysis for more than six months and who signed the informed consent form. Patients will be allocated into two groups: respiratory muscle training with PowerBreath and control. All will be evaluated for demographic data, respiratory muscle strength, lung function, functional capacity and quality of life. The intervention group will perform three months of intradialytic training of a physical therapy protocol with PowerBreath. Both groups will be reevaluated after three months.

Enrollment

46 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients with chronic kidney disease undergoing hemodialysis for more than 6 months Both genders
  • ged 18 years or older
  • clinically stable
  • who agreed to participate in the study by signing a free informed consent form

Exclusion criteria

  • Patients with previous or current myoarticular or neurological disease;
  • That require some urgent or elective surgical intervention during the protocol;
  • Any cardiac decompensation such as arrhythmias, systolic blood pressure greater than 200mmHg or less than 60mmHg, diastolic blood pressure greater than 120mmHg or less than 40mmHg;
  • Decompensated diabetes mellitus and acute systemic infection

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

46 participants in 2 patient groups

Respiratory muscle training
Experimental group
Description:
- three months of intradialytic training of a physical therapy protocol with PowerBreath.
Treatment:
Other: Respiratory muscle training
Control
No Intervention group
Description:
No intervention

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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