Respirophasic Carotid Artery Peak Velocity Variation as a Predictor of Fluid Responsiveness in Patients With Coronary Disease

Yonsei University

Status: Completed

Conditions: Coronary Artery Occlusive Disease

Treatments: Other: Volume expansion

Study type: Interventional

Funder types: Other

Identifiers

NCT01836081

4-2011-0687

Details and patient eligibility

About

The aim of this study is to investigate usefulness of the respirophasic variation in carotid artery peak flow velocity measured by Doppler ultrasound, which is noninvasive and easily accessible, as a predictor of fluid responsiveness in patients with coronary artery disease.

Enrollment: 40 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. patients scheduled for elective isolated off-pump coronary artery bypass graft surgery

Exclusion criteria

1. cardiac rhythm other than sinus
2. congestive heart failure
3. left ventricular ejection fraction <35%
4. history of transient ischemic attack
5. pre-existing cerebrovascular disease and peripheral arterial occlusive disease
6. presence of carotid artery stenosis >50%

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

fluid responsiveness

Experimental group

Treatment:

Other: Volume expansion