Response Evaluation in Malignant Pleural Mesothelioma

Istituto Clinico Humanitas

Status: Unknown

Conditions: Malignant Pleural Mesothelioma

Study type: Observational

Funder types: Other

Identifiers

NCT00969098

ONC/OSS-02/2009

Details and patient eligibility

About

Recently, a few small trials have shown promising results on value of fluoro-2-deoxy-D-glucose and positron emission tomography imaging in response assessment in Malignant Pleural Mesothelioma. These studies considered different parameters in Positron Emission Tomography (PET) analysis, mainly the standardized uptake value and volume-based parameters such as total glycolytic volume.

Full description

This is a retrospective analysis of two consecutive and homogeneous series of Malignant Pleural Mesothelioma patients treated with first-line pemetrexed-based chemotherapy and evaluated by CT scan and FDG-PET.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histologically proven MALIGNANT PLEURAL MESOTHELIOMA
• Patients not candidate to radical surgery
• Unidimensionally and/or bidimensionally CT-measurable disease and Candidate to first-line pemetrexed-based chemotherapy

Exclusion criteria

• Histologically not proven MALIGNANT PLEURAL MESOTHELIOMA