Response Inhibition in Tourette Syndrome

Cincinnati Children's Hospital Medical Center

Status: Completed

Conditions: Tourette Syndrome

Treatments: Device: Repetitive TMS

Study type: Interventional

Funder types: Other

Identifiers

NCT03628703

CIN001 - TAA2018

Details and patient eligibility

About

Tics are the hallmark symptoms in Tourette Syndrome. Patients with Tourette Syndrome have difficulties controlling unwanted movements. The ability to control the motor system involves the pre-supplementary motor area (pre-SMA) in the brain. In this study, we will use Transcranial Magnetic Stimulation to modulate the pre-SMA and determine effect on the ability to stop an unwanted action in a behavior task (stop signal task).

Enrollment: 10 patients

Sex: All

Ages: 10 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Tourette Syndrome

Exclusion criteria

• Autism spectrum disorder
• Mood disorder
• Epilepsy
• Implanted medical device (e.g. pacemaker, shunt, pumps)

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Repetitive TMS

Experimental group

Description:

Repetitive Intermittent Theta-Burst Transcranial Magnetic Stimulation

Treatment:

Device: Repetitive TMS