Response Prediction After GKS in Patients With Vestibular Schwannoma Using DCE MR Imaging

Seoul National University

Status: Unknown

Conditions: Vestibular Schwannoma

Study type: Observational

Funder types: Other

Identifiers

NCT03097822

H-1611-087-809

Details and patient eligibility

About

Response Prediction after Gamma Knife Surgery (GKS) in Patients with Vestibular Schwannoma using Dynamic Contrast-Enhanced (DCE) MR Imaging

Full description

The purpose of this study was to evaluate the response of Gamma Knife Surgery to Ktrans, Ve, and Vp, which are indicators of permeability map obtained from dynamic contrast enhanced (DCE) MRI in patients with vestibular schwannoma .

Enrollment: 90 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with vestibular schwannoma, who underwent gamma knife surgery and pre-op dynamic contrast enhanced (DCE) MRI
• Patients with vestibular schwannoma, who received consent

Exclusion criteria

• In addition to the vestibular schwannoma, if the brain has other underlying or systemic disease
• During the observation period, other treatments were performed other than gamma knife surgery
• If patients have a contraindication to MRI (eg, pacemaker, cochlear implants, hemodynamically unstable)
• Concomitant use of gadolinium MRI contrast agents (eg, renal insufficiency [glomerular filtration rate <30 ML / min]), or if there was a side effect when using a contrast medium.
• Adults with impaired ability to cope
• If the images and medical records required for this study are not available or are not appropriate