Response to Periodontal Therapy in a Chronic Kidney Disease Population

Pontificia Universidad Catolica de Chile

Status: Unknown

Conditions: Periodontal Disease; Chronic Kidney Disease Stage 5

Treatments: Procedure: Non Surgical Periodontal Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT03525457

180104004

Details and patient eligibility

About

This study will evaluate periodontal and systemic parameters of a cohort of chronic kidney disease (stage 5) patients, before and three months after non-surgical periodontal treatment. It does not consider a control group.

Full description

Dental biofilm is a source of inflammation and infection of periodontal tissues. In the last 20 years the interaction between periodontal infections and systemic conditions has been largely studied, suggesting that the inflammation caused in the periodontal tissues could cause a response in other parts of the body.

Recent studies suggest that there could be an association between periodontal disease and chronic kidney disease.

Enrollment: 65 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chronic kidney disease patients in Stage 5 (candidates to renal transplant)

Exclusion criteria

• Younger than 18 year old.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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65 participants in 1 patient group

Experimental

Experimental group

Description:

Non surgical periodontal therapy

Treatment:

Procedure: Non Surgical Periodontal Therapy