Response to SLT vs. ALT in Patients Under 60 Years of Age

Sunnybrook Health Sciences Centre

Status: Completed

Conditions: Glaucoma

Treatments: Procedure: Selective laser trabeculoplasty; Procedure: Argon laser trabeculoplasty

Study type: Interventional

Funder types: Other

Identifiers

NCT01087684

459-2004

Details and patient eligibility

About

Laser trabeculoplasty is a routine treatment for glaucoma and can be performed with either argon (ALT) or selective Yag (SLT) lasers. The effectiveness of each has not been studied in patients under 60 years, which is younger than average for the procedure. The study hypothesis is that there will be no difference between the two laser types.

Full description

Forty-two young patients (age 29 to 60) had one eye randomized to ALT (n = 22) or SLT (n = 20). Intraocular pressure was measured prior to laser and 1 hour, 1 day, 6 weeks, 3 months, every 3 months until 2 years, and then yearly post-laser. χ2 analysis and student's t-test were used to determine statistical significance.

Enrollment: 42 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age < 60 years
• Intraocular pressure not adequately controlled

Exclusion criteria

• Prior laser treatment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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42 participants in 2 patient groups

Argon laser trabeculoplasty

Active Comparator group

Description:

Patients received standard argon laser treatment

Treatment:

Procedure: Argon laser trabeculoplasty

Selective laser trabeculoplasty

Active Comparator group

Description:

Patients received a standard selective laser treatment

Treatment:

Procedure: Selective laser trabeculoplasty