Resting Metabolic Rate, Fat Distribution, Endocrine and Metabolic Features in Polycystic Ovary Syndrome

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Completed

Conditions: Polycystic Ovary Syndrome

Treatments: Diagnostic Test: SenseWear Armband (SWA) monitoring; Diagnostic Test: total body dual-energy X-ray absorptiometry

Study type: Observational

Funder types: Other

Identifiers

NCT03132545

ARMOC

Details and patient eligibility

About

In a longitudinal, prospective and observational study, patients with PCOS and controls wore the SenseWear Armband for 2 days. Resting metabolic rati (kcal/die), total energy expenditure (MET, kcal) were evaluated. Ultrasonographic pelvic examinations, hirsutism score, anthropometric and menstrual pattern evaluation, hormonal profile assays, oral glucose tolerance test (OGTT) and lipid profile were performed.

Enrollment: 160 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• . PCOS diagnosed according with the Rotterdam Consensus Conference criteria

Exclusion criteria

• presence of a late-onset adrenal enzyme defect
• Significant liver or renal impairment
• pregnancy and nursing
• neoplasm
• cardiovascular disease
• other hormonal dysfunctions

Trial design

160 participants in 2 patient groups

PCOS

Treatment:

Diagnostic Test: SenseWear Armband (SWA) monitoring

Diagnostic Test: total body dual-energy X-ray absorptiometry

controls

Treatment:

Diagnostic Test: SenseWear Armband (SWA) monitoring

Diagnostic Test: total body dual-energy X-ray absorptiometry