Results of Different Location of Ahmed Glaucoma Valve Implantation in Refractory Glaucoma, Superior Versus Inferior

Shahid Beheshti University of Medical Sciences

Status: Completed

Conditions: Glaucoma

Treatments: Procedure: AGV implantation

Study type: Interventional

Funder types: Other

Identifiers

NCT00628173

8417

Details and patient eligibility

About

Purpose:To compare the efficacy and safety of Ahmed Glaucoma Valve (AGV) implantation in the superior versus inferior quadrants.

Methods: In a non-randomized clinical trial and over a period of two years, consecutive patients with refractory glaucoma underwent AGV implantation in the superior or inferior quadrants. Main outcome measures included best corrected visual acuity (BCVA), intraocular pressure (IOP), number of glaucoma medications, complications and success rate (defined as at least 30% IOP reduction below preoperative values and 5<IOP<22 mmHg with or without glaucoma medications). Other criteria for failure included implant removal, additional glaucoma surgery, phthisis bulbi or loss of light perception.

Enrollment: 106 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with refractory glaucoma who need AGV implantation

Exclusion criteria

• Eyes with less than 3 months follow-up
• Severe conjunctival adhesions and scarring for the site of surgery
• Presence of thin sclera and staphyloma for the site of surgery
• The presence or anticipated need for silicone oil for superior implantation
• Active neovascular glaucoma for inferior implantation

Trial design

106 participants in 2 patient groups

1

Experimental group

Description:

patients with refractory glaucoma who were candidate for AGV implantation allocated in superior site

Treatment:

Procedure: AGV implantation

2

Experimental group

Description:

patients with refractory glaucoma who were candidate for AGV implantation allocated in inferior site

Treatment:

Procedure: AGV implantation