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The purpose of this study is to determine whether resveratrol is effective in the treatment of painful knee osteoarthritis.
Full description
Osteoarthritis (OA) is the first cause of handicap in individuals over 40 years-old in France. OA physiopathology is driven in part by local joint inflammation responsible for pain and joint destruction. Experimental studies have shown that resveratrol, a molecule antagonist to the aryl hydrocarbon receptor, has anti-inflammatory and chondroprotective properties in vitro and in vivo. The investigators hypothesize that oral resveratrol, in a new formulation improving its bioavailability, could reduce knee pain at 3 months as compared with placebo in people with knee OA.
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142 participants in 2 patient groups, including a placebo group
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Data sourced from clinicaltrials.gov
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