Retinal Function in Relation to Long Term Changes in the Glucose Level

Glostrup University Hospital, Copenhagen

Status: Unknown

Conditions: Diabetes Mellitus

Treatments: Other: Insulin pump

Study type: Observational

Funder types: Other

Identifiers

NCT00973401

Holfort

Details and patient eligibility

About

The purpose of this study is to measure the amplitude and implicit time of electroretinogram (ERG), darkadaptation and the calibre of retinal vessels before and after optimized medical treatment of diabetic individuals (a lower blood glucose level) over a period of 12 months. Newly diagnosed type 1 and type 2 diabetics as well as dysregulated type 1 and type 2 diabetic individuals will be included. Retinal vessel calibre measurements will be used as an estimation of changes in the retinal perfusion.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Dysregulated type 1 diabetic individuals and newly diagnosed type 1 diabetics. Age >17 < 60 years

Exclusion criteria

• Test individuals with significant cataract, prior surgery to the eye, diabetic retinopathy, other serious eye disease, hypertension, other serious systemic disease.

Trial design

30 participants in 1 patient group

Diabetic individuals

Treatment:

Other: Insulin pump