Retinal Nerve Fiber Layer Thickness Analysis With Cirrus HD OCT Versus Stratus Optical Coherence Tomography (OCT)

Yonsei University

Status: Unknown

Conditions: Glaucoma

Study type: Observational

Funder types: Other

Identifiers

NCT00766389

3-2008-0113

Details and patient eligibility

About

The Cirrus HD OCT, a new spectral domain optical coherence tomography (OCT), has better resolution than the previous time domain Stratus OCT. Discriminating ability of these two OCTs for diagnosis of glaucoma and judgement of disease progression will be studied.

Full description

The Cirrus HD OCT is a new spectral domain OCT. Even though its resolution and speed are much better than the previous time domain Stratus OCT, its diagnostic power for glaucoma detection and judgement of disease progression should be directly compared with Stratus OCT. In the present study, we will review the data of peripapillary retinal nerve fiber layer thickness measurement using the Cirrus HD OCT and Stratus OCT. Their discriminating ability for diagnosis of glaucoma and judgement of disease progression will be compared using the ROC curves and Cohen's kappa.

Enrollment: 200 estimated patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Retinal nerve fiber layer analysis with Cirrus OCT and Stratus OCT within 1 month

Exclusion criteria

• Intraocular surgeries history
• DM
• High refractive error ( < -4.00 diopters, or > + 4.00 diopters)
• Media opacity

Trial design

200 participants in 2 patient groups

1

Description:

Defined glaucoma patients

2

Description:

Glaucoma suspects and normal controls