Retinal Therapy Guided by 3D OCT Image Analysis

Michael Abramoff

Status: Completed

Conditions: Choroidal Neovascularization; Age-Related Macular Degeneration

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT02308215

1R01EY019112-01A2 (U.S. NIH Grant/Contract)

201003712

Details and patient eligibility

About

The main purpose is to find a better way to predict the timing of treatments given to patients with Wet Age-related macular degeneration using image analysis.

Full description

The study focuses on making better use of advanced three-dimensional imaging and analysis to allow physicians to know when a treatment is being effective and thus not overuse it. The study will examine how 3-D optical coherence tomography and related image analysis can be used to assess changes in the macula and retina of patients' eyes. These changes can reveal how well a person is responding to anti-VEGF treatment and thus help doctors provide proper treatment timing and care.

Enrollment: 77 patients

Sex: All

Ages: 45 to 120 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• fundoscopically confirmed AMD and patient eligible for treatment with anti-VEGF

Exclusion criteria

• Patients with a CNV due to other causes (OHS, trauma)
• eyes that have been previously treated for CNV