Retrospective Analysis of Procedural Aspects of Transcatheter Aortic Valve Implantation (TAVI) on Peri-procedural Stroke

Royal Sussex County Hospital

Status: Unknown

Conditions: Aortic Valve Stenosis

Treatments: Procedure: Balloon Aortic Valvuloplasty

Study type: Observational

Funder types: Other

Identifiers

NCT02711540

TAVIStrokePredictors

Details and patient eligibility

About

Retrospective analysis of all patients receiving TAVI in the United Kingdom (UK). Stroke rates following TAVI are roughly 3%. There are several device and procedure related characteristics which may increase the risk of stroke. We will examine if there is a signal in the UK registry. This will be important is TAVI is to be extended down to lower risk patient cohorts.

Full description

Retrospective analysis of all patients receiving TAVI in the UK. Stroke rates following TAVI are roughly 3%. There are several device and procedure related characteristics which may increase the risk of stroke. We will examine if there is a signal in the UK registry. This will be important is TAVI is to be extended down to lower risk patient cohorts.

Factors to be examined include (but not limited to):

need for Pre-procedure Balloon aortic Valvuloplasty (BAV) Need for two valves need for post-dilatation need for rapid ventricular burst pacing

Enrollment: 4,000 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Had TAVI procedure in UK

Exclusion criteria

• Nil

Trial design

4,000 participants in 2 patient groups

Pre-TAVI Balloon Aortic Valvuloplasty

Description:

This is the cohort of patients in the study who did receive Balloon Aortic Valvuloplasty (BAV) prior to TAVI implantation

Treatment:

Procedure: Balloon Aortic Valvuloplasty

No Pre-TAVI Balloon Aortic Valvuloplasty

Description:

This is the cohort of patients in the study who did not receive Balloon Aortic Valvuloplasty (BAV) prior to TAVI implantation