Retrospective Cohort Observational Study to Evaluate the Effectiveness and Safety of Fresh or Frozen Embryo Transfer

LG Chem

Status: Completed

Conditions: Infertility, Female

Treatments: Drug: rFSH

Study type: Observational

Funder types: Industry

Identifiers

NCT05130125

LG-IMHOS001

Details and patient eligibility

About

A multicenter, retrospective cohort observational study to evaluate the effectiveness and safety of fresh or frozen embryo transfer after ovarian hyperstimulation (administration of rFSH or HP-hMG alone or co-administration of rFSH and HP-hMG)

Full description

A multicenter, retrospective cohort observational study to evaluate the effectiveness and safety of fresh or frozen embryo transfer after ovarian hyperstimulation (administration of rFSH or HP-hMG alone or co-administration of rFSH and HP-hMG) to infertile female patients undergoing assisted reproductive technology to controlled ovarian hyperstimulation

Enrollment: 1,166 patients

Sex: Female

Ages: 19 to 39 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• First IVF-ET cycle patients

Exclusion criteria

Poor ovarian responder

• At least two of the following three features must be present: (i) Advanced maternal age (≥ 40 years) or any other risk factor for Poor ovarian response (POR); (ii) A previous POR (≤ 3 oocytes with a conventional stimulation protocol); (iii) An abnormal ovarian reserve test (i.e. AFC < 5-7 follicles or AMH < 0.5-1.1 ng/mL)

Trial design

1,166 participants in 2 patient groups

fresh embryo

Description:

fresh embryo transfer after ovarian hyperstimulation

Treatment:

Drug: rFSH

frozen embryo

Description:

frozen embryo transfer after ovarian hyperstimulation

Treatment:

Drug: rFSH