Retrospective Identification of Scintigraphic Cardiac Amyloidosis (RISCA)

University Hospital, Lille

Status: Not yet enrolling

Conditions: Transthyretin Amyloidosis; Cardiac Amyloidosis

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT06921408

2024_0111

ID RCB Number (Other Identifier)

Details and patient eligibility

About

This study aims to determine the positive predictive value of incidental cardiac uptake on bone scintigraphy for diagnosing transthyretin cardiac amyloidosis, in patients who underwent scintigraphy for reasons other than suspected amyloidosis. The study is an observational, descriptive, multicenter, national study using retrospective data from routine care. Patients with incidental cardiac uptake will be recalled for further diagnostic assessment.

Enrollment: 57 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults (≥ 18 years)
• Patients who underwent bone scintigraphy with 99mTc-HMDP/DPD/PYP for any indication
• Incidental cardiac uptake (Perugini grade ≥2) confirmed by a nuclear medicine specialist

Exclusion criteria

• Patients under legal protection
• Patients refusing the reuse of their data after individual information