Retrospective Review of CT and MR in Pediatric Patients With Cholestasis

National Taiwan University

Status: Unknown

Conditions: Children; Cholestasis

Study type: Observational

Funder types: Other

Identifiers

NCT01252043

201010044R

Details and patient eligibility

About

The investigators will try to predict the risk of esophageal varices (EVs) in long-term BA survivors using noninvasive computed tomography (CT) or magnetic resonance (MR) indices and the measurement of transverse diameters of paraesophageal and gastroesophageal veins.

Full description

We intend to review retrospectively 80 pediatric patients on an average of 2 years, who underwent 64-slice CT or MR examinations between January 2005 and Oct 2010 and had EVs on esophagogastroduodenoscopy. Splenic diameters (mm) and hepatic diameters of all patients were measured. Splenic and hepatic volume indices also calculated. The transverse diameters of paraesophageal varices (PVs) and perigastric varices (PGVs) were measured adjacent to the lower thoracic esophagus and within the lesser sac, respectively.

We will try to find out the possible splenic, hepatic or vascular predicting factors useful to evaluate the risk of clinically evident esophageal varices.

Enrollment: 80 estimated patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all cholestatic children with CT, MR and complete medical record

Exclusion criteria

• all cholestatic children without either CT, MR or complete medical record

Trial design

80 participants in 3 patient groups

cohort

Description:

cholestatic children without esophageal variceal bleeding

study

Description:

cholestatic children with esophageal variceal bleeding

cholestatic children without EV

Description:

cholestatic children without esophageal variceal bleeding