Retrospective Study of Patients with Acute Presentation for Asthma to an Emergency Department in UK (RAPAE)

Norfolk and Norwich University Hospitals NHS Foundation Trust

Status: Not yet enrolling

Conditions: Asthma Acute

Study type: Observational

Funder types: Other

Identifiers

NCT06360185

Asthma V2 October 2023

Details and patient eligibility

About

Study team will obtain a list of all patients who have been seen in A+E over the past 6 years with a discharge diagnosis of asthma. Their history will be reviewed from their A+E notes. Team will obtain weight and height from Electronic prescribing tool and will obtain compliance information and past medical history from participant's GP records. Team will use participant's postcode to word out socio economic status quintile using office of national statistics tool. The following information will be taken from hospital documentation and from GP records.

Full description

1. How many previous admissions in past one year (12 months)
2. How many presentations to A+E in previous one year (12 months)
3. Diagnosis not confirmed therefore not on any ICS
4. Poor compliance (less than 75% of ICS and/or LABA and/or LAMA and/or leukotriene prescriptions picked up in past year)
5. Recent presentation and maintenance therapy not increased (primary care or secondary care issue)
6. Is patient overweight BMI
7. Is patient on hormonal therapy, OCP, HRT, male hormones
8. Social class quintile from post code of address using ONS calculator
9. Ethnically diverse (see appendix)
10. First Eosinophil count on index admission
11. Highest eosinophil count in past (ever) and date
12. Treatment for diabetes type 2
13. Treatment for diabetes type 1
14. Treatment for hypertension
15. Smoker ever (pack year) when gave up__________

After obtaining this information study team will use simple statistical methods such as frequency and associations with confidence intervals to investigate which factors are associated with frequency of presentation to A+E. They will ascertain the frequency of patients who are on maximum therapy and may benefit from biological therapy, especially if they have raised eosinophils in the past year.

Enrollment: 400 estimated patients

Sex: All

Ages: 16 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All Asthmatics patients who attend Emergency department over 5 years

Exclusion criteria

• None Asthmatics.

Trial design

400 participants in 1 patient group

Asthmatics presenting to the emergency department in NNUH over 5 years

Description:

Asthmatics presenting to the emergency department in NNUH over 5 years