Retrospective Study to Describe Carfilzomib Use on Patients With Relapsed Multiple Myeloma in France in the Context of Carfilzomib Nominative Expanded Access and Compassionate Use (CARMYN)

Centre Hospitalier le Mans

Status: Completed

Conditions: Relapsed Multiple Myeloma

Study type: Observational

Funder types: Other

Identifiers

NCT04811508

CHM-2020/S14/07

Details and patient eligibility

About

This retrospective multicenter observational study will provide real-life efficacy and tolerance data for patients with relapsed multiple myeloma (RMM) treated with carfilzomib in the context of nominative expanded access and compassionate use in France, and will allow to evaluate healthcare practices from data obtained during the use of carfilzomib for routine care. Nominative expanded access was open in February 2014 and stopped in march 2016, then relayed by the compassionate program (march 2016- February 2017).

Enrollment: 172 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male or female patients over the age of 18 years
• Patients beginning carfilzomib treatment in the framework of expanded access or compassionate use in France (KRd or Kd regimen)
• Patients who received carfilzomib in first or second MM relapse
• Patients receiving at least one complete course of carfilzomib

Exclusion criteria

• Patients already included in an interventional research protocol using carfilzomib at the time of treatment initiation
• Patients refusing to allow the computerization of their data
• Patients for whom hospital medical records are not accessible