Retrospective Study to Evaluate the Feasibility of Ovarian Preservation in Patients With Endometrial Carcinoma (ECWOP)

Taipei Veterans General Hospital

Status: Unknown

Conditions: Endometrial Cancer

Treatments: Procedure: surgery

Study type: Observational

Funder types: Other

Identifiers

NCT01560026

VHG0500

Details and patient eligibility

About

Endometrial cancer is one of the most common female malignancies in the United States, and has increased in incidence in Taiwan in recent decades.A recent population-based analysis noted that 4% of endometrial cancers occurred in women aged 40 years or younger, furthermore it is up to 15% in Taiwan according to the data of cancer registry. The standard treatment of endometrial cancer results in surgical menopause and places patients at risk for the long-term sequelae of estrogen deprivation. The goal of this study was to determine the frequency of a coexisting ovarian malignancy and to evaluate the outcome of ovarian preservation in women with treatment for endometrial cancer.

Full description

we reviewed the cases with early stage of endometrial cancer who have primary staging surgery between January 1989 to December 2009. The enrolled patients will be divided into two group (oophorectomy vs. ovary preservation) for analysis:the outcome and recurrence type.To evaluate the outcome of ovarian preservation in women with endometrial cancer .

Enrollment: 300 estimated patients

Sex: Female

Ages: 25 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• early stage endometrial cancer after primary surgery exclusion criteria:
• MMMT, type 2 endometrial cancer

Trial design

300 participants in 2 patient groups

ovarian preservation

Description:

endometrial cancer with ovarian preservation

Treatment:

Procedure: surgery

oophorectomy

Description:

endometrial cancer without ovarian preservation