Retrospective Study to Review Patients at Risk for VTE at Hospital Discharge

Mass General Brigham

Status: Completed

Conditions: Venous Thromboembolism

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT00604370

2006-P-001981

Details and patient eligibility

About

An investigator initiated study exploring VTE prophylaxis at the time of hospital discharge.

Full description

It appears likely that many patients will remain at risk for VTE at the time of hospital discharge. These risks will go unrecognized, and discharge prophylaxis orders will not be prescribed.

To test this hypothesis, we will perform a retrospective review of approximately 2,500 patients at Brigham and Women's Hospital at risk for VTE at the time of hospital discharge to determine what proportion received VTE prophylaxis. We will correlate the implementation of discharge VTE prophylaxis with the occurrence of symptomatic DVT and pulmonary embolism within 90 days of hospital discharge.

We will also conduct a substudy of this patient population to determine adherence to VTE prophylaxis among hospitalized patients.

Enrollment: 2,500 patients

Sex: All

Ages: 17+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acutely ill medical and surgical patients with a risk score of 4 or greater without prophylaxis or a risk score of 4 or greater with anticoagulation at hospital discharge.

Exclusion criteria

• None.

Trial design

2,500 participants in 2 patient groups

1

Description:

Acutely ill medical and surgical patients who were hospitalized at BWH, and at-risk for VTE, but were not treated with prophylaxis at hospital discharge.

2

Description:

Acutely ill medical and surgical patients who were at risk for VTE at time of hospital discharge and prescribed a prophylaxis strategy.