Revascularization of Single Vesrus Multiple Infrapopliteal Vessels in Chronic Limb Threatening Ischemia

Sohag University

Status: Enrolling

Conditions: Chronic Limb Threatening Ischemia; Infrapopliteal Arterial Occlusive Disease

Treatments: Procedure: balloon angioplasty

Study type: Interventional

Funder types: Other

Identifiers

NCT07068789

Soh-Med-25-6-14MS

Details and patient eligibility

About

This interventional prospective study aims to assess the effectiveness of single vessel versus multiple vessel infrapopliteal angioplasty in patients with chronic threatening limb ischemia . The study compares limb salvage rates and clinical outcomes across two groups over a defined follow up period

Enrollment: 40 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: 1. patients aged 40 years or older 2. patients with Rutherford category "4" and "5" 3. patients with angiographic evidence of infrapopliteal vessel occlusive disease -

Exclusion Criteria:

1. patients who refuse to participate in the study
2. patients with isolated proximal arterial disease (e.g SFA or popliteal ) without infrapopliteal involvement
3. patients who develop acute thrombosis , flow limiting dissection or perforation in the infrapopliteal arteries during intervention -

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 3 patient groups

three vessel revascularization

Experimental group

Description:

patients in this group will undergo will receive angioplasty of all three infrapopliteal arteries

Treatment:

Procedure: balloon angioplasty

two vessel revascularization

Experimental group

Description:

patients in this group will undergo will receive angioplasty of two infrapopliteal arteries

Treatment:

Procedure: balloon angioplasty

single vessel revascularization

Experimental group

Description:

patients in this group will undergo will receive angioplasty of only one infrapopliteal artery

Treatment:

Procedure: balloon angioplasty