Revascularization of Young Immature Permenant Teeth Using Different Types of Intra Canal Medication

Al-Azhar University

Status: Not yet enrolling

Conditions: Traumatic Teeth; Necrotic Teeth

Treatments: Drug: Glycyrrhizin; Drug: Triple Antibiotic Paste; Drug: Grape Seed Extract

Study type: Interventional

Funder types: Other

Identifiers

NCT07236567

Revascularization

Details and patient eligibility

About

Evaluation of the Effect of Grape Seed Extract, Glycyrrhizin Compared to Triple Antibiotic Paste as Intra Canal Medication in Revascularization of Necrotic Permanent Immature Teeth in Children: A Randomized Clinical Trial

Full description

Digital count of e.faecalis before and after application of different type of intra canal medication

Enrollment: 45 estimated patients

Sex: All

Ages: 7 to 13 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Healthy children aged from 7-13 years old.
• Patient with necrotic pulp.
• Open apex.

Exclusion Criteria:.

• Teeth with root fractures.
• Presence of root resorptions.
• Presence of periodontal pockets.
• Developmental anomalies.
• Tooth with class III mobility

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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45 participants in 3 patient groups

Group a

Active Comparator group

Description:

Revascularization with triple antibiotic paste as intracanal medication

Treatment:

Drug: Triple Antibiotic Paste

Group b

Experimental group

Description:

Revascularization with grape seed extract as intra canal medication

Treatment:

Drug: Grape Seed Extract

Group c

Experimental group

Description:

Revascularization with glycyrrhizin as intracanal medication

Treatment:

Drug: Glycyrrhizin