Reverse Trendelenburg Position Versus Semi-recumbent Position in Obese Critically Ill Patients

Alexandria University

Status: Completed

Conditions: Critically Ill; Ventilation and Oxygenation; Obese; Positioning

Treatments: Other: Reverse Trendelenburg position; Other: Semi-recumbent position

Study type: Interventional

Funder types: Other

Identifiers

NCT04376047

1212020

Details and patient eligibility

About

The aim of this study is to assess the effect of reverse Trendelenburg position versus semi-recumbent position on ventilation and oxygenation parameters of obese critically ill patients

Full description

Obese critically ill patients' position significantly impacts on their ventilation and oxygenation status. It is also associated with mechanical ventilation success or failure and may be a main determinant of the obese patients' outcome. Reverse Trendelenburg position is recommended for obese patients but in critical illness with mechanical ventilation little is known about its effect on respiratory therapeutic targets. This trial was conducted in four general intensive care unit of Alexandria Main University hospital in Alexandria, Egypt. One hundred and ten adult mechanically ventilated patients with body mass index ≥ 30 were randomly assigned by a computer program to either reverse Trendelenburg position group (n=55) which is the intervention group or semi-recumbent position group (n=55) which is the routine unit position. Patients were positioned in the study positions 4 times per day. Patients were maintained in the study positions for 2 hours each time. Baseline ventilation and oxygenation parameters were assessed immediately before positioning then it was reassessed every 10 minutes after positioning for 30 minutes.

Enrollment: 110 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• body mass index ≥ 30
• Mechanically ventilated

Exclusion criteria

• Trauma
• Shock
• Acute respiratory distress syndrome

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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110 participants in 2 patient groups

Reverse Trendelenburg position group

Experimental group

Description:

Obese critically ill patients who are positioned in reverse Trendelenburg position

Treatment:

Other: Reverse Trendelenburg position

Semi-recumbent position group

Active Comparator group

Description:

Obese critically ill patients who are positioned in semi-recumbent position which is the routine ICU position

Treatment:

Other: Semi-recumbent position