Reviving Early Diagnosis of Cardiovascular Disease in the Utrecht Health Project (RED-LRGP)

UMC Utrecht

Status

Invitation-only

Conditions

Coronary Artery Disease

Atrial Fibrillation

Valvular Heart Disease

Heart Failure

Treatments

Diagnostic Test: Early diagnosis strategy

Study type

Interventional

Funder types

Other

Identifiers

NCT05775354

NL82944.041.23

Details and patient eligibility

About

The goal of this randomized trial is to compare the diagnostic yield of a screen-like early diagnosis strategy to usual primary care to detect coronary artery disease (CAD), atrial fibrillation (AF), heart failure (HF), and/or valvular heart disease (VHD) in community people aged 50-80 years who participate in the Utrecht Health Project.

The diagnosis strategy consists of a questionnaire with questions related to symptoms suggestive of CAD, AF or HF, a focused physical examination, laboratory testing, electrocardiography, and echocardiography.

Enrollment

1,476 estimated patients

Sex

All

Ages

50 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Aged 50-80 years
Being a participant of LRGP
Having indicated in the LRGP informed consent to be interested in participating in further research.

Exclusion criteria

Diagnosed with coronary artery disease and atrial fibrillation and heart failure.
Undergoing major (cardiovascular) surgery, and/or revascularisation therapy and/or transplantation treatment within 3 months after enrolment.
Not willing to give written informed consent for RED-LRGP.
Not allowing incidental findings to be reported to him/herself or their own GP.