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Rewards Sensitivity After Brain Injury

Shirley Ryan AbilityLab logo

Shirley Ryan AbilityLab

Status

Completed

Conditions

Acquired Brain Injury

Treatments

Behavioral: Type of reward presented

Study type

Interventional

Funder types

Other

Identifiers

NCT06510023
STU00213877

Details and patient eligibility

About

A study measuring rewards sensitivity in individuals with acquired brain injury at an acute rehabilitation level.

Full description

Individuals in acute rehabilitation following acquired brain injury journal (ABI) and aged-matched, non-injured controls will be recruited for this study.

Testing sessions will take place in a private treatment room at the Shirley Ryan AbilityLab and required 45 minutes to complete. Upon entering the room, participants will be greeted, electrodes placed on the participant's fingers to record their electrodermal activity, and participants will provide demographic information. Participants will then be instructed about how to respond on the Cued Reinforcement Response Time task (CRRT, see description below), and complete the task on a laptop computer while their electrodermal activity is being recorded. In this task, they are instructed to respond as quickly and accurately as possible, and will be informed that they will receive a monetary reward based on their accuracy at the completion of the task. Finally, participants will complete 3 self-report measures: (1) explicit level of motivation was measured in a post-study survey which included two items from the Sensitivity to Punishment and Sensitivity to Reward Questionnaire, (SPSRQ); (2) Reward sensitivity was evaluated using the Reward Responsiveness Scale , and (3) depression was evaluated using the Patient Health Questionnaire (PHQ-8) survey. At the end of the session, the electrodes will be removed, and participants will be debriefed and provided their monetary reward

Enrollment

31 patients

Sex

All

Ages

18 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Individuals with ABI

    • Diagnosis of Traumatic Brain Injury or Stroke, based on their medical records
    • Age between 18-100
    • Able to follow directions in English (measured informally during screening)
    • Able to use at least one upper extremity (demonstrated by holding a pen)
    • Mild-moderate or lesser diagnosis in cognitive-communication area
    • Score of 25 or higher on the Orientation Log assessment
    • Able to consent for participation in study (identifies through chart review)
    • Capable of understanding and cooperating with the experimental procedures.

Healthy participants

  • Age of 18 to 100 years old
  • Ability to follow directions in English
  • Ability to use at least one upper extremity.

Exclusion criteria

  • Individuals with ABI

    • Additional diagnosis of a neurological disorder other than ABI
    • Additional diagnosis of aphasia.
    • Having cognitive or behavioral impairments that preclude participation in the experimental procedures

Healthy Participants

• history of significant cerebrovascular or neurological disease including (but not limited to) meningitis, epilepsy and/or seizures, stroke, tumor, multiple sclerosis, meningitis, mental retardation, dementia.

Trial design

Primary purpose

Basic Science

Allocation

Non-Randomized

Interventional model

Factorial Assignment

Masking

None (Open label)

31 participants in 2 patient groups

Individuals with Acquired Brain Injury
Experimental group
Description:
Measuring the effect of three different types of rewards (one dollar, one penny, and no reward) on performance in a cognitive test.
Treatment:
Behavioral: Type of reward presented
Non-impaired controls
Other group
Description:
Measuring the effect of three different types of rewards (one dollar, one penny, and no reward) on performance in a cognitive test.
Treatment:
Behavioral: Type of reward presented

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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