RFA and Bite Force in COD Teeth

Eskisehir Osmangazi University

Status: Completed

Conditions: Cemento-Osseous Dysplasia; Jaw Diseases / Diagnosis; Tooth Ankylosis

Treatments: Diagnostic Test: Bite Force Sensor; Diagnostic Test: Resonance Frequency Analysis (RFA)

Study type: Interventional

Funder types: Other

Identifiers

NCT07185711

EskisehirOU-Dereci-001

Details and patient eligibility

About

This study aims to evaluate the periodontal attachment and ankylosis status of teeth associated with cemento-osseous dysplasia (COD). Using resonance frequency analysis (RFA) and a bite force sensor, the stability of COD-associated teeth was measured and compared with contralateral healthy teeth. These non-invasive and objective methods are expected to reveal the impact of COD lesions on the surrounding dentoalveolar structures.

Full description

Cemento-osseous dysplasias represent the most common group of benign fibro-osseous lesions, frequently detected in the mandible and often asymptomatic. Although they generally do not require treatment, the remodeling of bone and cementum-like tissues around the tooth roots has clinical significance in terms of periodontal attachment and ankylosis. The present study aims to investigate the ankylosis status of teeth associated with COD lesions at different stages by using objective measurement tools.

In each patient, COD-associated teeth and contralateral healthy teeth were evaluated. Measurements were performed using resonance frequency analysis (RFA) with the Osstell™ device and additionally by a bite force sensor to assess functional stability. For RFA, SmartPeg magnetic attachments were fixed to the occlusal surface with composite resin, and three measurements were obtained in both mesio-distal and bucco-lingual directions. Mean ISQ values were then recorded. After measurements, SmartPeg was carefully removed without leaving residues, and patient comfort was evaluated using a six-point numeric rating scale.

The obtained RFA and bite force values will be statistically analyzed to compare COD-associated teeth with healthy controls. Furthermore, the study seeks to determine differences in ankylosis tendency across various COD stages and their potential impact on periodontal ligament integrity. This approach may provide valuable insights for understanding the clinical course of COD and for planning surgical interventions in symptomatic cases

Enrollment: 17 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients diagnosed with cemento-osseous dysplasia (COD) based on panoramic radiographs
• Presence of at least one COD-associated tooth suitable for measurement
• Availability of a contralateral healthy tooth to serve as a control
• Teeth with healthy periodontal supporting tissues
• Patients aged ≥18 years
• Patients who have provided written informed consent

Exclusion criteria

• Presence of systemic diseases that could affect bone or periodontal structures (e.g., uncontrolled diabetes, osteoporosis, metabolic bone diseases)
• History of radiotherapy or chemotherapy in the head and neck region
• Teeth with extensive caries, mobility, or periodontal disease
• Patients with a history of orthodontic treatment or trauma in the relevant region

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Parallel Assignment

Masking: None (Open label)

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17 participants in 2 patient groups

Arm 1: Teeth with Cemento-Osseous Dysplasia

Experimental group

Description:

Teeth associated with cemento-osseous dysplasia were evaluated using Resonance Frequency Analysis (RFA) and a bite force sensor to assess ankylosis and stability.

Treatment:

Diagnostic Test: Resonance Frequency Analysis (RFA)

Diagnostic Test: Bite Force Sensor

Arm 2: Healthy Contralateral Teeth (Control Group)

Active Comparator group

Description:

Healthy contralateral teeth from the same patients, without cemento-osseous dysplasia, were evaluated using the same methods (RFA and bite force sensor) for comparison with COD-associated teeth.

Treatment:

Diagnostic Test: Resonance Frequency Analysis (RFA)

Diagnostic Test: Bite Force Sensor