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Rheumatoid Arthritis Patients in Training (RAPIT)

L

Leiden University Medical Center (LUMC)

Status and phase

Unknown
Phase 4

Conditions

Rheumatoid Arthritis

Treatments

Procedure: long-term intensive exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT00434200
OG-97-024

Details and patient eligibility

About

Aim of the study was to investigate the effectiveness (functional ability and physical capacity) and safety (disease activity and damage of the joints) of long-term high-intensity weight-bearing exercises in patients with rheumatoid arthritis (RA).The training proved to be safe and effective.

Full description

The 300 patients with RA were randomized into two groups; exercise group and usual care group. The patients who participated in the 2 years intensive exercise training (2 times a week, training duration 65 minutes) improved their functional capacity and functional ability without detrimental effects on the large joints damage or on disease activity. Only patients with excessive large joint damage at baseline were at risk to develop additional damage when participating in intensive weight-bearing exercises. Patients who exercised were able to delay the decrease of bone mineral density of the hips.

Sex

All

Ages

17 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Rheumatoid arthritis

Exclusion criteria

  • Prosthesis of a weight bearing joint

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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