Rhinosinusites Chroniques

Institut Hospitalo-Universitaire Méditerranée Infection

Status: Unknown

Conditions: Chronic Disease; Refractory; Sinusitis

Treatments: Other: Biological sample

Study type: Interventional

Funder types: Other

Identifiers

NCT02407275

IHU Méditerranée Infections

Details and patient eligibility

About

To analyse and describe sinus microbiota, during hard to treat (or refractory) rhinosinusitis, using culturomic and metagenomic methods (i.e. to culture on many different medium of culture to grow hard to cultivate bacteria + to sequence and analyse all DNA contained in samples).

Samples are middle meatus swabs or pus aspiration, done during usually patient following.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >18 year old
• chronic refractory rhinosinusitis
• to require middle meatus swab or other sinus sample
• absence of opposition

Exclusion criteria

• <18 year old
• pregnant women
• breastfeeding
• under trusteeship
• under guardianship

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

biological sample

Other group

Description:

Genomic \& culturomic analyses

Treatment:

Other: Biological sample