Rhomboid Intercostal and Subserratus / Paravertebral Block

Bursa Uludag University

Status: Not yet enrolling

Conditions: Thoracic; Analgesia; Anesthesia

Treatments: Procedure: RHOMBOID INTERCOSTAL AND SUBSERRATUS PLANE BLOCK; Procedure: PLACEBO; Procedure: PARAVERTEBRAL BLOCK

Study type: Interventional

Funder types: Other

Identifiers

NCT06253741

2022-17/23

Details and patient eligibility

About

Postoperative pain is a significant concern following video-assisted thoracoscopic surgery (VATS). Pain after thoracic surgery not only causes a strong stress reaction and adverse emotional experience but also affects postoperative rehabilitation. Hence, different analgesia techniques, including local anesthetic infiltration, intercostal nerve block, paravertebral block, and thoracic epidural anesthesia, have been described to attenuate the intensity of acute postoperative painparavertebral block (PVB) and Rhomboid intercostal block with sub-serratus plane block (RISS) are the two types of plane blocks used for postoperative analgesia after video-assisted thoracoscopic surgery (VATS). This prospective randomized controlled trial was performed to analyze the postoperative analgesic effects of ultra- sound-guided PVB and RISS block after video-assisted thoracoscopic surgery.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Planned for VATS
• American Society of Anesthesiologists (ASA) class I and II
• Patients aged between 18-80

Exclusion criteria

• Contraindications to local anesthetic allergy or bupivacaine
• Known or suspected coagulopathy
• Injection site infection
• History of thoracic surgery
• Severe neurological or psychiatric disorder
• Severe cardiovascular disease
• Liver failure
• Renal failure (glomerular filtration rate <15 ml/min/1.73 m2)
• Chronic opioid use

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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30 participants in 3 patient groups, including a placebo group

PARAVERTEBRAL BLOCK

Active Comparator group

Description:

After induction of general anesthesia and endotracheal intubation in the operating room, following the positioning of the patient for surgery, ultrasound-guided paravertebral block (PVB) will be routinely performed in our clinic using 0.25% bupivacaine solution at a dose of 0.5 ml/kg.

Treatment:

Procedure: PARAVERTEBRAL BLOCK

RHOMBOID INTERCOSTAL AND SUBSERRATUS PLANE BLOCK

Active Comparator group

Description:

After induction of general anesthesia and endotracheal intubation in the operating room, following the positioning of the patient for surgery, rhomboid intercostal block with sub-serratus plane block (RISS) will be routinely performed in our clinic using 0.25% bupivacaine solution at a dose of 0.5 ml/kg under ultrasound guidance.

Treatment:

Procedure: RHOMBOID INTERCOSTAL AND SUBSERRATUS PLANE BLOCK

PLACEBO

Placebo Comparator group

Description:

The group without any peripheral block application will be included

Treatment:

Procedure: PLACEBO