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RHYTHMIC STIMULUS EFFECTS ON NEURONAL OSCILLATORY ACTIVITY AND SPEACHES CAPABILITIES IN DEAF CHILDREN

P

Public Assistance-Hospitals of Marseille (AP-HM)

Status

Unknown

Conditions

Children Deafness

Treatments

Other: musical rhythmic stimulation

Study type

Interventional

Funder types

Other

Identifiers

NCT02901691
2015-31
2015-A01490-49 (Other Identifier)

Details and patient eligibility

About

The deaf children showed deficits in speech processing and temporality. They badly apprehend temporal concepts and perceptions of deficit so the acoustic phenomena marking the time course linguistically. Their prediction capabilities and anticipation multisensory events are thereby affected, thus impacting their ability to adapt to multiple and complex interaction possibilities that arise during a conversation.The project aim it is to measure the impact of a musical rhythmic stimulation of neuronal activity and the temporal prediction capabilities of older deaf children 5 to 8 years and its impact on their language skills in a conversational task. A matched control group of age will be examined for each of the proposed tasks.

We first measure the capacity to anticipate a situation of language interaction. For this purpose, we will use an alternate naming paradigm with a virtual partner, already developed and tested in children with normal hearing. This paradigm approaches the conversational situation while allowing control of the time parameter of speech (speed of trade) and by controlling the bias (temporal) inherent linguistic programming difficulties of children in a spontaneous conversation situations .

Then we will couple behavioral measurements with measurements of eye movements and the electroencephalogram (EEG) in deaf children. For this, we use a dialog observation task already developed for normal hearing children. This task will allow us firstly to analyze the anticipation level of speaking turns by analyzing eye movements (which "precedes" the speaker). Secondly, it will allow us to study the effects of manipulation of the acoustic parameters of auditory evoked potentials (AEP) and the oscillatory activity of the motor system (EEG, mu rhythm and beta). The audiomoteur coupling would seem to be the key point of anticipatory processes and convergence in conversational interaction will also be studied using cortico-cortical coherence techniques to assess the dynamics of connectivity between remote networks (system here auditory and motor system).

Enrollment

60 estimated patients

Sex

All

Ages

4 to 9 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • prélingual paired deaf or implanted cochlear children.

Exclusion criteria

  • Childreen with other major disabilities and associated disorders.
  • Clidren with failure to understand instructions either directly oral or sign language.

Trial design

Primary purpose

Supportive Care

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

60 participants in 2 patient groups, including a placebo group

Deaf children
Experimental group
Treatment:
Other: musical rhythmic stimulation
healthy volonteer children
Placebo Comparator group
Treatment:
Other: musical rhythmic stimulation

Trial contacts and locations

1

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Central trial contact

Stéphane Roman, MD

Data sourced from clinicaltrials.gov

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