Ridge Augmentation With Simultaneous Implant Placement Using Bone Blocks With Autogenous Tooth Graft

Kafrelsheikh University

Status: Completed

Conditions: Ridge Augmentation; Implant; Autogenous Tooth Graft

Treatments: Procedure: ABB and ABG with simultaneous implant placement; Procedure: XBB and ATG with simultaneous implant placement; Procedure: ABB and ATG with simultaneous implant placement

Study type: Interventional

Funder types: Other

Identifiers

NCT05407363

KFSIRB200-72

Details and patient eligibility

About

Autogenous bone, with its osteogenic, osteoinductive, and osteo-conductive characteristics has been used for bone grafts with optimal integration into host tissues. For this reason, autogenous bone has been often considered the gold standard of bone regeneration material. However, the amount of autogenous bone that may be harvested is limited, and the harvesting procedure is traumatic.

Bone substitutes, including allografts, xenografts, and alloplasts have been used successfully as alternatives to autogenous bone grafts in ridge augmentation procedures.

In 2008, autogenous tooth bone graft (ATG) was introduced and used for the first time as a bone grafting material for GBR. The tooth contents are extremely similar to that of the alveolar bone. The enamel inorganic, organic, and water contents are 95 percent, 0.6 percent, and 4 percent, respectively. However, in the dentin, the percentages are 70 to 75 percent, 20 percent, and 10 percent, respectively. They are 65 percent, 25 percent, and 10 percent, respectively, when compared to the alveolar bone content.

The aim of this study is to compare ridge augmentation using autogenous bone block (ABB) with immediate implant placement and filling the generated gap with autogenous bone graft (ABG) or ATG, or ridge augmentation using xenograft bone block (XBB) with immediate implant placement and filling the generated gap with ATG.

Enrollment: 30 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Teeth with buccal bone destruction by periodontal disease and need extraction (horizontal or vertical bone defect);
• Absence of acute inflammation;
• Absence of uncontrolled systemic illness that would preclude implantation;
• Good dental and systemic healthy conditions;
• Patients were willing and able to return for multiple follow-up visits.

Exclusion criteria

• Patients with systemic illnesses,
• psychological abnormalities,
• para-functional habit,
• smokers or alcoholics,
• pregnant and lactating patients,
• patients undergoing or recently completed radiotherapy or chemotherapy,
• patients on drugs affecting the healing process,
• patients with endodontically treated teeth

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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30 participants in 3 patient groups

ABB and ATG with simultaneous implant placement

Experimental group

Description:

Using ABB with ATG to fill the gap around simultaneously placed dental implants

Treatment:

Procedure: ABB and ATG with simultaneous implant placement

XBB and ATG with simultaneous implant placement

Experimental group

Description:

Using XBB with ATG to fill the gap around simultaneously placed dental implants

Treatment:

Procedure: XBB and ATG with simultaneous implant placement

ABB and ABG with immediate implant

Active Comparator group

Description:

Using ABB with ABG to fill the gap around immediately placed dental implants

Treatment:

Procedure: ABB and ABG with simultaneous implant placement