Right Lateral Positioning and Its Effect on Induction of General Anesthesia for Children

Assiut University

Status and phase: Completed; Phase 2

Conditions: Anesthesia

Treatments: Procedure: Right lateral position; Procedure: supine position

Study type: Interventional

Funder types: Other

Identifiers

NCT02654184

IRB000087118

Details and patient eligibility

About

The quality of induction with sevoflurane, along with its ability to generate optimal conditions for Laryngeal Mask Airway (LMA) insertion without supplemental opioids or muscle relaxants, has also been well documented. An ideal inhalation induction technique besides being rapid and comfortable for the patient should be economical. To achieve rapidity, use of vital capacity breaths with 8% sevoflurane is a more popular method of induction compared with the conventional incremental induction.

Full description

100 pediatric patients (age range, 1 to 8 years) scheduled for lower abdominal surgery under anesthesia will be included. All children in both groups will be premedicated with midazolam, 0.5 mg/kg orally, about 30 minutes before the induction of anesthesia. A parent or guardian accompanied the child into the operating room to allow the child to remain calm and cooperative for inhalation induction. Before induction, pulse oximetry and electrocardiogram monitoring will be attached. For each group, inhalation induction was initiated using a face mask using "tidal volume" and "vital capacity" breathing in high sevoflurane concentration (8%).

Enrollment: 100 patients

Sex: All

Ages: 1 to 8 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children aged 1 years to 8 years
• Children with ASA class I/II and their willingness to participate in the study

Exclusion criteria

• Known seizure disorder
• Craniofacial abnormalities/difficult airway
• Cardiopulmonary or neuromuscular defects
• Hepatic or renal insufficiency
• Expected difficult intravenous (IV) cannulation (eg, dark complexion, obese)
• Catching colds during the past four weeks

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

Supine group

Active Comparator group

Description:

Anesthesia induction with sevoflurane for the patient while he is in supine position.

Treatment:

Procedure: supine position

Right lateral group

Active Comparator group

Description:

Anesthesia induction with sevoflurane for the patient while he is in right lateral position position.

Treatment:

Procedure: Right lateral position