Right Ventricular Function in Heart Failure

shaimaa Mostafa

Status: Completed

Conditions: Assessment of the RV Function in Patients With Heart Faliure

Treatments: Diagnostic Test: echocardiography

Study type: Observational

Funder types: Other

Identifiers

NCT03641599

RV

Details and patient eligibility

About

Only a few studies evaluated the RV systolic function in the three categories of HF, regarding the importance of understanding changes in RV function on clinical presentation and outcome; it was essential to understand the prevalence and severity of RV dysfunction among the three groups and the degree of correlation between RV with LV systolic function.

Enrollment: 150 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Adult patients of both gender who have the followiong criteria :

(i) symptoms with or without signs of HF (ii) elevated natriuretic peptides (BNP ≥35pg/ mL or NT-proBNP≥125pg/mL) (iii) relevant structural heart disease: left ventricle hypertrophy (left ventricular mass index ≥115 g/m2 for males and ≥95 g/m2 for females) or left atrial enlargement (>34 mL/m2) or diastolic dysfunction (E/e'≥13 and a mean e' septal and lateral wall <9 cm/s) were included.

Then patients were classified according to EF into HFpEF>50%, HFrEF<40% and HFmrEF >40% and <50%

Exclusion criteria

Patients with chronic obstructive pulmonary disease history of pulmonary embolism patients with respiratory failure

Trial design

150 participants in 3 patient groups

heart failure with preserved ejection fraction

Treatment:

Diagnostic Test: echocardiography

heart failure with mid range ejection fraction

Treatment:

Diagnostic Test: echocardiography

heart failure with reduced ejection fraction

Treatment:

Diagnostic Test: echocardiography