Right Ventricular Function in Patients With Obstructive Sleep Apnea

Associação Fundo de Incentivo à Pesquisa

Status: Completed

Conditions: Obstructive Sleep Apnea

Study type: Observational

Funder types: Other

Identifiers

NCT01201200

Eco2

Details and patient eligibility

About

The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in right ventricular function evaluated by three dimensional echocardiography.

Full description

Several studies have reported the association between sleep disorders to an increased risk to the development of cardiac disease. However, there is no substantial that about the influence of Obstructive Sleep Apnea on the right ventricular function. Objective: to analyse the right ventricular function in patients with Obstructive Sleep Apnea by means of Real-Time Three dimensional Echocardiography.

Enrollment: 106 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Individuals > 18 years old and < 70.

Exclusion criteria

• Body mass index greater than 35
• Past of clinically significant cardiac conditions

Trial design

106 participants in 4 patient groups

Group 1 - Obstructive Sleep Apnea (OSA)

Description:

Fifty-six patients with Obstructive Sleep Apnea

Group 2 - Non-OSA Controls

Description:

Fifty individuals without OSA with similar age, gender and body mass index (BMI)

Group 3 - Treatment

Description:

Fifteen patients with moderate and severe sleep apnea from group 1 underwent treatment with continuous positive airway pressure

Group 4 - Placebo

Description:

Fifteen patients with moderate/severe sleep apnea underwent to placebo