Risk Factor for Readmission and Death of Lower Respiratory Infections in Older Adults

Capital Medical University

Status: Completed

Conditions: Anemia; Death; Lower Respiratory Infection; Readmission

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT05355324

YuHe_1987

Details and patient eligibility

About

Lower respiratory tract infection(LRTI) is a prevalent disease that threatens the health of older people worldwide. Anemia is also a common disorder in the elderly, and its prevalence increases significantly with age. Most factors that contribute to the development of anemia are improvable. Therefore, we investigated whether anemia was a risk factor for LRTI-caused readmission and death in the elderly occurring within 1 year of discharge from the hospital.

Full description

Objectives: To investigate the effect of anemia on readmission and deaths in the older adults following lower respiratory tract infection (LRTI)-caused hospitalization.

Design: A retrospective cohort study. Setting and Participants: Older patients (age: ≥ 80 years) hospitalized at the Department of Geriatrics, from March 2016 to December 2019 to undergo treatment for LRTIs were included.

Methods: The patients were divided into two groups (anemia and non-anemia) based on the level of hemoglobin. They were kept under observation till the occurrence of mortality event or 1 year after discharge. The primary follow-up outcome was LRTI-caused readmission and/or death.

Enrollment: 215 patients

Sex: All

Ages: 80 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 80 years
• lower respiratory tract infection

Exclusion criteria

• Died at the time of first admission
• Active malignancy
• Tuberculosis
• Anemia caused by gastrointestinal bleeding of unknown origin
• Achalasia of the cardia
• Could not be followed up after discharge
• Data were missing

Trial design

215 participants in 2 patient groups

anemia

Description:

patients with anemia

Treatment:

Other: no intervention

non-anemia

Description:

patients without anemia

Treatment:

Other: no intervention