Risk Factors Affecting Mortality in Perforated Peptic Ulcer

Maharajgunj Medical Campus

Status: Completed

Conditions: Peptic Ulcers

Treatments: Procedure: Emergency laparotomy

Study type: Observational

Funder types: Other

Identifiers

NCT07050199

PG-NMC/528/078-079

Details and patient eligibility

About

Perforation is one of the most severe and life-threatening complications of peptic ulcer disease. This study aims to evaluate the risk factors associated with postoperative morbidity and mortality in patients undergoing surgery for peptic ulcer perforation, with a focus on the timing of presentation, demographic variables, surgical delay, and their association with postoperative outcomes.

Enrollment: 85 patients

Sex: All

Ages: 15 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with peptic ulcer perforation aged> 15 years and <75 years.
• Patients with duodenal or gastric perforation of peptic ulcer origin.
• Patients who underwent simple closure with omental patch as a standard operative procedure.

Exclusion criteria

• Patients treated with conservative management.
• Patients with perforation of peptic ulcer origin at the jejunum, ileum adjacent to Meckel's diverticulum.
• Patients presenting with recurrent perforation or stomal ulcer perforation.

Trial design

85 participants in 1 patient group

Patients with peptic ulcer perforation of age > 15 years and <75 years

Treatment:

Procedure: Emergency laparotomy