Risk Factors and Prediction Score of ARDS After Cardiac Surgery

Capital Medical University

Status

Completed

Conditions

Respiratory Distress Syndrome, Adult

Risk Factors

Thoracic Surgery

Treatments

Other: no intervention

Study type

Observational

Funder types

Other

Identifiers

NCT02759770

Shoufa-2016-2-1052

Details and patient eligibility

About

Acute respiratory distress syndrome following cardiac surgery severely affects the prognosis of patients; the mortality is up to 40%. Although experience many years of research and exploration, the effective methods for the treatment of acute respiratory distress syndrome is still relatively limited at present, including lung protective mechanical ventilation respiratory support, fluid management, glucocorticoid and other integrated organ function maintenance measures. It is currently the research of acute respiratory distress syndrome aims at the early discovery and takes effective measures to prevent its occurrence, hoping to improve the prognosis of patients. According to risk factors is established through the analysis of lung injury score early warning system, the early identification of acute respiratory distress syndrome patients at high risk, before the occurrence of acute respiratory distress syndrome take corresponding preventive measures can effectively reduce the incidence rate and mortality. So far, domestic and foreign research on the establishment of acute respiratory distress syndrome scoring early warning system is less. Cardiac surgery has significant characteristics, type of operation, location, operation, intraoperative blood transfusion and oxygenation, postoperative factors, are likely to be the factors of acute respiratory distress syndrome. As far as investigators know, so far there are few specialized for acute respiratory distress syndrome predicting lung injury after cardiac surgery. This study will be completed after the implementation of individualized dynamic lung injury score evaluation of cardiac surgery patients, identification of high-risk acute respiratory distress syndrome patients, to assist clinicians in early decision, take preventive measures. This study will improve the prognosis of acute respiratory distress syndrome patients after cardiac surgery; it is of great significance to improve the level of intensive care after cardiac surgery.

Enrollment

1,333 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

Retrospective group: cardiac surgery patients accepted from Jan 2013 to Dec 2015
Prospective group: cardiac surgery patients accepted from 2017 January to December

Exclusion criteria

refused to participate in the study
age less than 18 years old
before operation performed mechanical ventilation
before operation underwent IABP treatment
before operation continuous renal replacement therapy
before operation undergoing in vitro membrane oxygenator treatment
before operation has the pulmonary imaging showed bilateral pulmonary diffuse exudation of interstitial pneumonia, pulmonary infection or respiratory failure
the major trauma, sepsis, aspiration, shock, acute heart failure
before operation diagnosed as malignant tumor
Incomplete data.