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Risk Factors and Treatment Outcome of Oncology Children Hospitalized in the Intensive Care Unit Due to Sepsis

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Clalit Health Services

Status

Unknown

Conditions

ICU
Childhood Cancer
Sepsis
Oncologic Complications and Emergencies

Treatments

Other: ICU treatment

Study type

Observational

Funder types

Other

Identifiers

NCT04032743
0590-18-RMC

Details and patient eligibility

About

Children treated with intensive chemotherapy are at increased risk for life-threatening infections (sepsis). As the survival of oncology patients increased with the use of aggressive treatment protocols, there was also an increase in the need for hospitalization in intensive care units (ICU) due to sepsis.Several prognostic factors are known to affect the survival of these patients, including the number and type of damaged systems, the type of oncology disease and the duration of neutropenia. With the development of the treatment of ICU, the survival of the oncology patients hospitalized for sepsis has also increased.

We will collect demographic details, details of their oncology and infections, laboratory tests and imaging. The goal is to identify prognostic factors in oncologic children hospitalized in ICU due to sepsis, as well as clinical and laboratory parameters that characterize this group of patients.

Enrollment

300 estimated patients

Sex

All

Ages

Under 19 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Treatment in the hemato-oncology for cancer
  • Admission to the ICU in SCMCI between 2008-2018 because of sepsis during chemotherapy

Exclusion criteria

  • Admission to the ICU more than 3 month after last chemotherapy or 1 year after SCT

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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