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Risk Factors for ARDS in Patients With Acute Necrotizing Pancreatitis

N

Nanjing Medical University

Status

Completed

Conditions

Acute Necrotizing Pancreatitis
Acute Respiratory Distress Syndrome

Study type

Observational

Funder types

Other

Identifiers

NCT02641964
JSSRMYY-HB-1

Details and patient eligibility

About

Try to collect about 350 cases of acute necrotizing pancreatitis at the First Affiliated Hospital with Nanjing Medical University and Nanjing General Hospital of Nanjing Military Command. Then the investigators studied the incidence and the risk factors of ARDS in patients with acute necrotizing pancreatitis.

Full description

Using electronic patient data monitoring systems, the investigators reviewed all patients with a diagnosis of pancreatitis admitted to surgical wards or ICUs at the First Affiliated Hospital with Nanjing Medical University and Nanjing General Hospital of Nanjing Military Command from January 1, 2009, to October 31, 2015. Inclusion criteria were adult patients (age >18 years) with acute necrotizing pancreatitis. Exclusion criteria were as follows : 1) lack of radiologic evidence to diagnose acute necrotizing pancreatitis, 2) presence of ARDS before admission to hospitals, 3) unable to partner treatment and leaving hospitals, 4) transferring to the investigators' hospitals after treatment, 5) missing other necessary data, and 6) pregnancy.

For enrolled patients, general clinical characteristics were collected. Patients were categorized into two groups according to ARDS or non-ARDS, and the differences of these characteristics between two groups were evaluated. Potential risk factors were collected and studied by using multiple logistic regression analysis.

Enrollment

350 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Adult patients (age >18 years) with acute necrotizing pancreatitis

Exclusion criteria

  • lack of radiologic evidence to diagnose acute necrotizing pancreatitis,
  • presence of ARDS before admission to hospitals,
  • unable to partner treatment and leaving hospitals,
  • transferring to the investigators' hospitals after treatment,
  • missing other necessary data,
  • pregnancy.

Trial design

350 participants in 2 patient groups

ARDS group
Description:
patients with acute necrotizing pancreatitis complicated by ARDS
non-ARDS group
Description:
acute necrotizing pancreatitis patients without ARDS

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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