Risk Factors for Community- and Workplace Transmission of COVID-19

University of Oslo (UIO)

Status: Enrolling

Conditions: Coronavirus

Treatments: Behavioral: Observation of behavior and COVID-19 infection will be conducted.

Study type: Observational

Funder types: Other

Identifiers

NCT04320732

REK-124170

Details and patient eligibility

About

The project is an epidemiological observational study based on an electronic questionnaire on risk factors for COVID-19 in the community and healthcare setting.

Full description

Summary The data collected will identify real-life risk factors for getting the COVID-19 diagnosis.

The Oslo University Hospital/University of Oslo web-based solution "nettskjema" will be used to collect data and consent forms.

The impact of knowing the risk factors for COVID-19 is tremendous because it can enable governments to conduct more targeted public health measurements than today to reduce the spread of the virus.

Detailed description Research into an ongoing COVID-19 outbreak is difficult because patients are isolated, and supplies of personal protective equipment (PPE) supplies are limited. The risk of transmission to study personal is non-negligible even when PPE is available.

A study design based on an electronic questionnaire and consent from delivered from the Oslo University Hospital/University of Oslo, GDPR (General Data Protection Regulation) compliant "TSD" service has therefore been chosen.

The study will be a case-control study based on a combined electronic consent form and questionnaire that the participants will fill in using a smartphone and electronic identification.

The groups that will be included are:

• Hospitalized and non-hospitalized patients/persons with COVID-19 at all stages of the disease and after the disease
• Hospitalized patients without COVID-19
• Healthcare personal or other groups with an increased risk of COVID-19
• Healthy volunteers

Participants may be followed with repeated questionnaires prospectively.

Biological samples Biological samples may hold crucial information about the susceptibility to COVID-19 and for susceptibility to the progression of the disease. It is within the scope of the study to analyze such samples from a limited number of participants which will be asked to provide such samples or hospitalized patients that have surplus material. The material will be analyzed with non-genetic methods most suitable to provide such information.

Enrollment: 250,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Norwegian adult

Exclusion criteria

• Unable to consent

Trial design

250,000 participants in 5 patient groups

Individuals with COVID-19 infection

Description:

Confirmed by routine laboratory diagnosis. All types of COVID-19 disease from asymptomatic carriers to hospitalized patients can be included. Only subjects \>18 years old will be included in the study.

Treatment:

Behavioral: Observation of behavior and COVID-19 infection will be conducted.

Individuals tested for COVID-19 infection with negative test

Description:

Confirmed by routine laboratory diagnosis

Treatment:

Behavioral: Observation of behavior and COVID-19 infection will be conducted.

Healthy individuals

Description:

Recruitet from the general population

Treatment:

Behavioral: Observation of behavior and COVID-19 infection will be conducted.

Risk groups for COVID-19 exposure

Description:

Including, but not limited to healthcare workers.

Treatment:

Behavioral: Observation of behavior and COVID-19 infection will be conducted.

Patients admitted to hospital

Description:

Without COVID-19 infection.

Treatment:

Behavioral: Observation of behavior and COVID-19 infection will be conducted.