Risk Factors for Development of Rapid Cycling in Bipolar Disorder Patients

Hospital Clinic of Barcelona

Status: Completed

Conditions: Bipolar Disorder

Study type: Observational

Funder types: Other

Identifiers

NCT01992302

RC-BBP

Details and patient eligibility

About

In this study we tried to elucidate the factors associated with the development of a rapid cycling course in bipolar disorder patients, in a prospective and longitudinal design, and the role of antidepressants. The identification of risk factors is extremely relevant from the clinical point of view. We hypothesized that rapid cycling bipolar disorder is associated with more chronicity, poor outcome, and more antidepressant prescription.

Enrollment: 289 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Bipolar I and II disorder patients according to DSM-IV criteria

Exclusion criteria

• Major medical comorbidities, voluntary drop-out from study

Trial design

289 participants in 2 patient groups

Rapid Cycling Group

Description:

Patients who develop a rapid cycling course during the follow-up period.

Non Rapid Cycling Group

Description:

Patients who do not develop a rapid cycling course during the follow-up period.